:root {
  color-scheme: light;
  --navy: #0e2841;
  --blue: #4a93e2;
  --teal: #4ea28d;
  --copy: #405368;
  --line: #dce5ed;
  --blue-tint: #f0f6fb;
  --teal-tint: #eef7f4;
  --soft-tint: #f6f8fa;
  font-family: Roboto, Arial, sans-serif;
  color: var(--navy);
  background: #fff;
  font-synthesis: none;
  text-rendering: optimizeLegibility;
}

* { box-sizing: border-box; }
html { scroll-behavior: smooth; }
body { margin: 0; font-size: 16px; line-height: 1.55; }
a { color: inherit; text-underline-offset: 4px; }
a:hover { text-decoration-thickness: 2px; }
a:focus-visible { outline: 3px solid #216bbc; outline-offset: 4px; border-radius: 2px; }
.page-shell { width: min(100% - 48px, 1024px); margin-inline: auto; }
.site-header { min-height: 106px; display: flex; align-items: center; justify-content: space-between; gap: 24px; border-bottom: 1px solid var(--line); }
.brand { display: inline-flex; flex: 0 1 180px; align-items: center; }
.brand img { display: block; width: 100%; height: auto; }
nav { display: flex; flex-wrap: wrap; align-items: center; gap: 12px 24px; }
nav a { text-decoration: none; }
.hero { padding: 60px 0 52px; }
.eyebrow { margin: 0 0 12px; color: #335f7f; font-weight: 700; letter-spacing: .06em; }
h1, h2, h3, p, figure { margin-top: 0; }
h1 { max-width: 790px; margin-bottom: 20px; font-size: 56px; font-weight: 400; letter-spacing: -.035em; line-height: 1.08; }
.hero-copy { max-width: 630px; margin-bottom: 0; color: var(--copy); }
.button { display: inline-flex; min-height: 48px; align-items: center; margin-top: 24px; padding: 10px 19px; background: var(--navy); color: #fff; font-weight: 700; text-decoration: none; }
.button:hover { background: #17476e; }
.hero-credibility { max-width: 700px; margin: 22px 0 0; color: var(--copy); }
.hero-credibility a { color: var(--navy); }
h2 { margin-bottom: 14px; font-size: 28px; font-weight: 500; letter-spacing: -.02em; line-height: 1.2; }
h3 { margin: 0 0 8px; font-size: 16px; font-weight: 600; line-height: 1.35; }
p, figcaption, nav, footer, .button, .organism-list, .stage-number, .full-matrix-link { font-size: 16px; }
.approach { display: grid; grid-template-columns: minmax(250px, .8fr) 1.35fr; gap: 34px 54px; padding: 36px 0 38px; border-top: 1px solid var(--line); }
.approach-intro { align-self: start; }
.approach-intro h2 { margin-bottom: 14px; }
.approach-lead { max-width: 400px; margin-bottom: 0; color: var(--copy); }
.approach-lead strong { font-weight: 700; }
.lineage-story { grid-column: 1 / -1; display: grid; grid-template-columns: minmax(0, 1fr) minmax(0, 440px); gap: 40px; align-items: center; }
.lineage-narrative { margin: 0; color: var(--copy); }
.lineage-narrative + .lineage-narrative { margin-top: 16px; }
.pedigree-figure { margin: 0; min-width: 0; }
.pedigree-figure picture, .pedigree-figure img { display: block; width: 100%; height: auto; }
figcaption { color: var(--copy); }
.approach-points { grid-column: 1 / -1; display: grid; grid-template-columns: repeat(3, minmax(0, 1fr)); gap: 24px; align-content: start; }
.approach-point { padding-top: 12px; border-top: 3px solid var(--teal); }
.approach-point:nth-child(2) { border-top-color: var(--blue); }
.approach-point:nth-child(3) { border-top-color: var(--navy); }
.approach-point p { margin-bottom: 0; color: var(--copy); }
.services { padding: 30px 0 40px; border-top: 1px solid var(--line); }
.services > h2 { margin-bottom: 18px; }
.service-panels { display: grid; grid-template-columns: repeat(2, minmax(0, 1fr)); }
.service-panel { min-height: 190px; padding: 25px 29px 28px; border-top: 4px solid var(--blue); background: var(--blue-tint); }
.service-panel + .service-panel { border-left: 1px solid #fff; }
.service-panel.service-teal { border-top-color: var(--teal); background: var(--teal-tint); }
.service-panel p { max-width: 460px; margin-bottom: 0; color: var(--copy); }
.how-we-work { padding: 35px 0 38px; border-top: 1px solid var(--line); }
.how-heading { display: grid; grid-template-columns: minmax(220px, .75fr) 1.25fr; column-gap: 50px; align-items: start; }
.how-heading h2 { grid-column: 1; grid-row: 1 / span 2; margin: 0; }
.how-heading h3 { grid-column: 2; margin-bottom: 8px; }
.how-heading > p { grid-column: 2; max-width: 660px; margin-bottom: 0; color: var(--copy); }
.project-stages { display: grid; grid-template-columns: repeat(3, minmax(0, 1fr)); margin-top: 28px; border-top: 1px solid var(--line); }
.project-stage { padding: 17px 22px 0 0; }
.project-stage + .project-stage { padding-left: 22px; border-left: 1px solid var(--line); }
.stage-number { display: block; margin-bottom: 8px; color: #286a59; font-weight: 700; letter-spacing: .05em; }
.project-stage p { margin-bottom: 0; color: var(--copy); }
.applications { padding: 34px 0 38px; border-top: 1px solid var(--line); }
.applications > h2 { margin-bottom: 18px; }
.application-list { border-top: 1px solid var(--line); }
.application-row { display: grid; grid-template-columns: minmax(250px, .8fr) 1.2fr; gap: 40px; align-items: start; padding: 13px 0; border-bottom: 1px solid var(--line); }
.application-row > p { margin: 0; color: var(--copy); }
.analysis-overview { display: grid; grid-template-columns: minmax(0, 360px) minmax(0, 1fr); align-items: center; gap: 40px; margin: 28px 0 0; }
.matrix-link { display: block; max-width: 360px; }
.matrix-link img { display: block; width: 100%; height: auto; }
.analysis-caption { color: var(--navy); font-weight: 600; }
.analysis-overview figcaption p { margin-bottom: 12px; }
.full-matrix-link { display: inline-block; color: #1d629f; }
.scope-highlights { display: grid; grid-template-columns: 1.25fr .75fr; background: var(--soft-tint); border-top: 3px solid var(--blue); }
.organisms, .products { padding: 26px 30px 28px; }
.products { border-left: 1px solid #fff; border-top: 3px solid var(--teal); margin-top: -3px; }
.scope-highlights h2 { margin-bottom: 18px; }
.organism-list { margin: 0; }
.organism-list > div { display: grid; grid-template-columns: 112px 1fr; gap: 12px; padding: 7px 0; border-top: 1px solid var(--line); }
.organism-list dt { color: var(--navy); font-weight: 700; }
.organism-list dd { margin: 0; color: var(--copy); }
.organism-note { margin: 14px 0 0; color: var(--copy); }
.products > p { margin: 0; color: var(--copy); }
.founder { display: grid; grid-template-columns: 180px minmax(0, 1fr); gap: 36px; align-items: start; padding: 36px 0; border-top: 1px solid var(--line); }
.founder-portrait { display: block; width: 180px; max-width: 100%; height: auto; }
.founder-copy h2 { margin-bottom: 8px; }
.founder-copy p { margin-bottom: 16px; color: var(--copy); }
.founder-copy .founder-role { color: var(--navy); font-weight: 600; }
.founder-copy a { color: #1d629f; }
.contact { display: flex; flex-wrap: wrap; justify-content: space-between; gap: 12px 24px; padding: 23px 0; border-top: 1px solid var(--line); }
.contact p { margin: 0; }
.contact a { color: #1d629f; }
footer { display: flex; flex-wrap: wrap; justify-content: space-between; gap: 12px 24px; padding: 0 0 22px; color: #53677b; }

@media (max-width: 900px) {
  .approach { grid-template-columns: 1fr; gap: 24px; }
  .lineage-story, .approach-points { grid-column: 1; }
  .approach-points { grid-template-columns: repeat(3, minmax(0, 1fr)); }
  .application-row { grid-template-columns: minmax(180px, .8fr) 1.2fr; gap: 24px; }
}

@media (max-width: 760px) {
  .page-shell { width: min(100% - 40px, 560px); }
  .site-header { min-height: 0; flex-wrap: wrap; gap: 14px; padding: 20px 0 15px; }
  .brand { flex-basis: 145px; }
  nav { width: 100%; justify-content: space-between; gap: 10px; }
  .hero { padding: 35px 0; }
  h1 { font-size: 38px; }
  h2 { font-size: 26px; }
  .approach { grid-template-columns: 1fr; gap: 20px; padding: 29px 0 31px; }
  .lineage-story { grid-template-columns: 1fr; gap: 16px; }
  .pedigree-figure { width: min(100%, 288px); justify-self: center; }
  .analysis-overview { grid-template-columns: 1fr; gap: 16px; }
  .analysis-overview .matrix-link { width: min(100%, 360px); justify-self: center; }
  .approach-points { grid-template-columns: 1fr; gap: 15px; }
  .approach-point { display: grid; grid-template-columns: minmax(145px, .75fr) 1.25fr; gap: 16px; padding-top: 10px; }
  .approach-point h3 { margin: 0; }
  .services { padding: 27px 0 32px; }
  .service-panel { min-height: 0; padding: 23px 22px 24px; }
  .how-we-work { padding: 29px 0 32px; }
  .how-heading { grid-template-columns: 1fr; gap: 0; }
  .how-heading h2, .how-heading h3, .how-heading > p { grid-column: 1; grid-row: auto; }
  .how-heading h2 { margin-bottom: 16px; }
  .project-stages { grid-template-columns: 1fr; margin-top: 22px; }
  .project-stage, .project-stage + .project-stage { display: grid; grid-template-columns: 42px 1fr; column-gap: 12px; padding: 15px 0; border-left: 0; border-bottom: 1px solid var(--line); }
  .stage-number { grid-row: 1 / span 2; margin: 1px 0 0; }
  .project-stage p { grid-column: 2; }
  .applications { padding: 29px 0 31px; }
  .application-row { grid-template-columns: 1fr; gap: 10px; padding: 13px 0; }
  .scope-highlights { grid-template-columns: 1fr; }
  .organisms, .products { padding: 24px 22px; }
  .products { border-left: 0; border-top: 1px solid #fff; margin-top: 0; }
  .founder { grid-template-columns: 140px minmax(0, 1fr); gap: 24px; padding: 27px 0; }
  .founder-portrait { width: 140px; }
}

@media (max-width: 430px) {
  .page-shell { width: min(100% - 36px, 380px); }
  .site-header { gap: 12px; }
  .brand { flex-basis: 135px; }
  nav { gap: 8px; }
  .hero { padding: 30px 0; }
  .service-panels { grid-template-columns: 1fr; }
  .service-panel + .service-panel { border-left: 0; border-top-width: 4px; }
  .approach-point { grid-template-columns: 1fr; gap: 3px; }
  .organism-list > div { grid-template-columns: 92px 1fr; gap: 8px; }
  .founder { grid-template-columns: 1fr; gap: 20px; }
  nav { justify-content: flex-start; column-gap: 16px; }
  .contact { padding: 21px 0; }
}

@media (prefers-reduced-motion: reduce) {
  html { scroll-behavior: auto; }
}

.application-group {
  margin-top: 24px;
}

.application-group + .application-group {
  margin-top: 36px;
}

.application-group-title {
  margin: 0 0 16px;
  padding-top: 12px;
  border-top: 3px solid var(--blue);
  font-size: 16px;
  font-weight: 700;
  line-height: 1.35;
}

.application-group-data .application-group-title {
  border-top-color: var(--teal);
}

.application-row h4 {
  margin: 0;
  font-size: 16px;
  font-weight: 600;
  line-height: 1.35;
}

.application-group-title {
  margin: 0 0 18px;
  padding-top: 14px;
  border-top: 3px solid var(--blue);
  font-size: 22px;
  font-weight: 700;
  line-height: 1.3;
}

.application-group-data .application-group-title {
  border-top-color: var(--teal);
}